CCR6 ligands inhibit HIV by inducing APOBEC3G
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چکیده
منابع مشابه
IMMUNOBIOLOGY CCR6 ligands inhibit HIV by inducing APOBEC3G
We have identified a postentry CCR6dependent mechanism of inhibition of HIV occurring at an early stage of infection mediated by the induction of the host restriction factor apolipoprotein B mRNAediting enzyme-catalytic polypeptide-like 3G (APOBEC3G). We observed induction of APOBEC3G expression only in CCR6 cells but not in cells treated with the G inhibitory (Gi) pathway inhibitor pertussis t...
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ژورنال
عنوان ژورنال: Blood
سال: 2010
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2009-06-226423